Bone Abstracts

Objective: Serotonin is a neurotransmitter with multiple functions in the gastrointestinal tract and CNS. Recent animal studies indicate that serotonin regulates bone mass and remodelling. In humans, a handful of studies have shown decreased bone mineral density (BMD) in adults treated with selective serotonin reuptake inhibitors (SSRI) for depressive symptoms. Although SSRI’s are prescribed in pediatric practice, there are few studies examining the effect of SSRIs on bon...